Collaborative Learning (Observational Study)

The Collaborative Learning study compared how well babies did after surgery at heart centers where babies were removed from the ventilator early (called early extubation and defined as within six hours of arrival to the ICU) versus at sites where babies were not taken off the ventilators early. This study also evaluated how well the heart centers followed the standard guidelines that were developed for postoperative extubation practices before the study started and during the study. The study assessed early extubation in infants with Tetralogy of Fallot or coarctation of the aorta.

Who was in the study?

Data were collected on babies who had Tetralogy of Fallot or coarctation of the aorta and who were undergoing surgical repair. These data were analyzed at sites which extubate their babies early compared to sites which did not extubate early to see if babies do the same, better or worse.

What happened in the study?

This study was a review of medical charts of infants from sites that extubated early as well as babies from sites that did not extubate early. Data collected included individual level data on sedation, pain scores, ventilator support, and length of stay; cost assessment data; and system level assessments.

What were the results of the study?

The collaborative learning strategy designed clinical practice guideline significantly increased the rate of early extubation with no change in the rate of reintubation. The early extubation clinical practice guideline did not significantly change postoperative ICU length of stay.